Changes

As a laxative, milk of magnesia absorbs fluid from the body, through osmotic pressure, into the lumen of the small intestine while retaining the fluid already in the small intestine (Pradyot, 2002). First, Mg2+ is poorly absorbed from the intestinal tract, so it draws water from the surrounding tissue by osmosis. Not only does this increase the water content, it softens the faeces and increases the volume of faeces in the intestine which naturally stimulates intestinal motility. Furthermore, Mg2+ ions cause the release of cholecystokinin (CCK) which results in intraluminal accumulation of water, electrolytes and increased intestinal motility. This stimulates the nerves of the colon to distend leading to peristalsis culminating in the evacuation of its contents.

As a laxative, milk of magnesia absorbs fluid from the body, through osmotic pressure, into the lumen of the small intestine while retaining the fluid already in the small intestine (Pradyot, 2002). First, Mg2+ is poorly absorbed from the intestinal tract, so it draws water from the surrounding tissue by osmosis. Not only does this increase the water content, it softens the faeces and increases the volume of faeces in the intestine which naturally stimulates intestinal motility. Furthermore, Mg2+ ions cause the release of cholecystokinin (CCK) which results in intraluminal accumulation of water, electrolytes and increased intestinal motility. This stimulates the nerves of the colon to distend leading to peristalsis culminating in the evacuation of its contents.

[[FIG 16]]

[[File:UNN_Medical_Geology_Fig_16.png|thumb|400px|{{figure number|16}}]]

===Plaster of Paris===

===Plaster of Paris===